/* ========== ORIGINAL HEADER STYLES ========== */
* {
    margin: 0;
    padding: 0;
    box-sizing: border-box;
    font-family: 'Segoe UI', Tahoma, Geneva, Verdana, sans-serif;
}

body {
    background-color: #f8f9fa;
    color: #333;
    display: flex;
    flex-direction: column;
    min-height: 100vh;
    overflow-x: hidden;
}

/* Header Styles */
.pamphlet-header {
    background: linear-gradient(135deg, #1a237e 0%, #283593 50%, #e53935 100%);
    color: white;
    padding: 60px 0 40px;
    text-align: center;
    box-shadow: 0 4px 12px rgba(0, 0, 0, 0.15);
    position: relative;
    overflow: hidden;
}

.pamphlet-header::before {
    content: "";
    position: absolute;
    top: 0;
    left: 0;
    width: 100%;
    height: 100%;
    background: url('data:image/svg+xml;utf8,<svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 1440 320"><path fill="%23ffffff" fill-opacity="0.1" d="M0,128L48,144C96,160,192,192,288,186.7C384,181,480,139,576,138.7C672,139,768,181,864,197.3C960,213,1056,203,1152,186.7C1248,171,1344,149,1392,138.7L1440,128L1440,320L1392,320C1344,320,1248,320,1152,320C1056,320,960,320,864,320C768,320,672,320,576,320C480,320,384,320,288,320C192,320,96,320,48,320L0,320Z"></path></svg>');
    background-size: cover;
    background-position: center;
    animation: wave 15s linear infinite;
}

@keyframes wave {
    0% {
        transform: translateX(0);
    }
    50% {
        transform: translateX(-5%);
    }
    100% {
        transform: translateX(0);
    }
}

.pamphlet-header h1 {
    font-size: 42px;
    font-weight: 700;
    margin-bottom: 12px;
    letter-spacing: 1px;
    text-transform: uppercase;
    position: relative;
    animation: fadeInDown 1s ease-out;
}

.pamphlet-header .subtitle {
    font-size: 18px;
    opacity: 0.9;
    font-weight: 300;
    letter-spacing: 0.5px;
    margin-bottom: 15px;
    position: relative;
    animation: fadeInUp 1s ease-out 0.3s both;
}

.breadcrumb {
    position: relative;
    margin-top: 10px;
    animation: fadeIn 1s ease-out 0.6s both;
}

.pamphlet-header a {
    display: inline-block;
    font-size: 14px;
    color: #fff;
    opacity: 0.85;
    text-decoration: none;
    transition: opacity 0.3s;
}

.pamphlet-header a:hover {
    opacity: 1;
}

.pamphlet-header a i {
    margin-right: 5px;
}

/* ========== CONTENT STYLES ========== */

.peptide-content-container {
    margin: 0 auto;
    flex: 1;
}

/* Introduction Section */
.peptide-introduction {
    padding: 50px;
}

.intro-wrapper {
    display: flex;
    align-items: center;
    gap: 60px;
}

.intro-text {
    flex: 1;
}

.intro-text h2 {
    color: #1a237e;
    font-size: 32px;
    margin-bottom: 20px;
    font-weight: 700;
}

.intro-text p {
    font-size: 18px;
    line-height: 1.8;
    color: #555;
    margin-bottom: 0;
}

.intro-visual {
    flex: 0 0 300px;
}

.peptide-structure {
    display: flex;
    align-items: center;
    justify-content: center;
    height: 120px;
}

.structure-node {
    width: 25px;
    height: 25px;
    background: #e8f4f8;
    border: 2px solid #1a237e;
    border-radius: 50%;
    position: relative;
    transition: all 0.3s ease;
}

.structure-node.active {
    background: #e53935;
    border-color: #e53935;
    transform: scale(1.2);
    box-shadow: 0 0 15px rgba(229, 57, 53, 0.3);
}

.structure-connector {
    width: 40px;
    height: 2px;
    background: linear-gradient(90deg, #1a237e, #e53935);
}

/* Content Sections Common Styles */
.content-section {
    padding: 20px;
}

.section-header {
    text-align: center;
    margin-bottom: 50px;
}

.section-icon {
    font-size: 48px;
    color: #e53935;
    margin-bottom: 20px;
}

.section-header h2 {
    color: #1a237e;
    font-size: 32px;
    margin-bottom: 20px;
    font-weight: 700;
}

.section-subtitle {
    font-size: 18px;
    line-height: 1.8;
    color: #666;
    max-width: 1400px;
    margin: 0 auto;
}

/* Synthesis Technology Section */
.technology-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 15px;
}

.tech-item {
    text-align: center;
    padding: 10px;
    background: #f8f9fa;
    border-radius: 10px;
    border: 1px solid #e8e8e8;
    transition: all 0.3s ease;
}

.tech-item:hover {
    transform: translateY(-5px);
    box-shadow: 0 10px 20px rgba(0, 0, 0, 0.1);
    border-color: #1a237e;
}

.tech-icon {
    width: 70px;
    height: 70px;
    background: linear-gradient(135deg, #1a237e, #283593);
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    margin: 0 auto 20px;
    color: white;
    font-size: 28px;
}

.tech-item h3 {
    color: #1a237e;
    font-size: 15px;
    margin-bottom: 15px;
    font-weight: 600;
    white-space: nowrap;
}

.tech-item p {
    color: #666;
    line-height: 1.6;
    font-size: 15px;
}

/* Manufacturing Infrastructure Section */
.infrastructure-details {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(250px, 1fr));
    gap: 30px;
}

.infrastructure-item {
    background: #f8f9fa;
    border-radius: 10px;
    padding: 25px;
    border: 1px solid #e8e8e8;
    transition: all 0.3s ease;
}

.infrastructure-item:hover {
    border-color: #1a237e;
    background: #f0f7ff;
}

.item-header {
    display: flex;
    align-items: center;
    gap: 15px;
    margin-bottom: 15px;
}

.item-icon {
    width: 50px;
    height: 50px;
    background: linear-gradient(135deg, #1a237e, #283593);
    border-radius: 10px;
    display: flex;
    align-items: center;
    justify-content: center;
    color: white;
    font-size: 22px;
    flex-shrink: 0;
}

.item-header h3 {
    color: #1a237e;
    font-size: 18px;
    font-weight: 600;
    margin: 0;
}

.infrastructure-item p {
    color: #666;
    line-height: 1.6;
    font-size: 15px;
    margin: 0;
}

/* Process Development Section */
.development-section {
    background: linear-gradient(135deg, #f8f9fa 0%, #e8f4f8 100%);
}

.development-process {
    display: grid;
    grid-template-columns: 1fr 1fr;
    gap: 30px;
    max-width: 1400px;
    margin: 0 auto;
}

.process-step {
    display: flex;
    align-items: flex-start;
    gap: 25px;
    padding: 25px;
    background: white;
    border-radius: 10px;
    border: 1px solid #e8e8e8;
    transition: all 0.3s ease;
}

.process-step:hover {
    border-color: #1a237e;
    transform: translateX(10px);
}

.process-step:last-child {
    margin-bottom: 0;
}

.step-number {
    width: 50px;
    height: 50px;
    background: linear-gradient(135deg, #1a237e, #283593);
    border-radius: 50%;
    display: flex;
    align-items: center;
    justify-content: center;
    color: white;
    font-size: 22px;
    font-weight: 700;
    flex-shrink: 0;
}

.step-content h3 {
    color: #1a237e;
    font-size: 18px;
    margin-bottom: 10px;
    font-weight: 600;
}

.step-content p {
    color: #666;
    line-height: 1.6;
    font-size: 15px;
    margin: 0;
}

/* Quality Control Section */
.quality-analysis {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(500px, 1fr));
    gap: 30px;
}

.analysis-methods h3,
.quality-assurance h3 {
    color: #1a237e;
    font-size: 24px;
    margin-bottom: 25px;
    font-weight: 600;
}

.methods-grid {
    display: grid;
    grid-template-columns: repeat(2, 1fr);
    gap: 20px;
}

.method {
    text-align: center;
}

.method-label {
    display: inline-block;
    background: linear-gradient(135deg, #1a237e, #283593);
    color: white;
    padding: 8px 20px;
    border-radius: 20px;
    font-weight: 700;
    font-size: 16px;
    margin-bottom: 15px;
}

.method p {
    color: #666;
    margin: 0;
    font-size: 15px;
}

.assurance-boxy {
    background: #f8f9fa;
    border-radius: 10px;
    padding: 25px;
    border: 1px solid #e8e8e8;
}

.assurance-list {
    list-style: none;
    padding: 0;
}

.assurance-list li {
    padding: 15px 0;
    border-bottom: 1px solid #e8e8e8;
    color: #555;
    font-size: 16px;
    display: flex;
    align-items: center;
    gap: 12px;
}

.assurance-list li:last-child {
    border-bottom: none;
}

.assurance-list i {
    color: #4caf50;
    font-size: 18px;
}

/* Quality Systems Section */
.systems-section {
    background: linear-gradient(135deg, #1a237e 0%, #283593 100%);
    color: white;
}

.systems-section .section-header h2,
.systems-section .section-subtitle {
    color: white;
}

.systems-section .section-icon {
    color: #ffcc00;
}

.systems-grid {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(350px, 1fr));
    gap: 30px;
}

.system-card {
    background: rgba(255, 255, 255, 0.1);
    border-radius: 10px;
    padding: 30px;
    border: 1px solid rgba(255, 255, 255, 0.2);
    transition: all 0.3s ease;
    backdrop-filter: blur(10px);
}

.system-card:hover {
    background: rgba(255, 255, 255, 0.15);
    transform: translateY(-5px);
    border-color: rgba(255, 255, 255, 0.3);
}

.card-header {
    display: flex;
    align-items: center;
    gap: 15px;
    margin-bottom: 20px;
}

.card-header i {
    font-size: 36px;
    color: #ffcc00;
}

.card-header h3 {
    font-size: 22px;
    margin: 0;
    font-weight: 600;
}

.system-card p {
    color: rgba(255, 255, 255, 0.9);
    margin-bottom: 20px;
    line-height: 1.6;
    font-size: 16px;
}

.card-features {
    list-style: none;
    padding: 0;
    margin: 0;
}

.card-features li {
    color: rgba(255, 255, 255, 0.9);
    padding: 8px 0;
    font-size: 15px;
    position: relative;
    padding-left: 20px;
}

.card-features li:before {
    content: "✓";
    position: absolute;
    left: 0;
    color: #4caf50;
    font-weight: bold;
}

/* Conclusion Section */
.conclusion-section {
    border-radius: 15px;
    padding: 20px 50px;
    text-align: center;
}

.conclusion-icon {
    font-size: 60px;
    color: #1a237e;
    margin-bottom: 25px;
}

.conclusion-section h2 {
    color: #1a237e;
    font-size: 36px;
    margin-bottom: 25px;
    font-weight: 700;
}

.conclusion-text {
    font-size: 18px;
    line-height: 1.8;
    color: #555;
    max-width: 800px;
    margin: 0 auto 40px;
}

.conclusion-cta {
    display: flex;
    gap: 20px;
    justify-content: center;
    flex-wrap: wrap;
}

.cta-button {
    display: inline-flex;
    align-items: center;
    gap: 12px;
    padding: 16px 32px;
    background: linear-gradient(135deg, #1a237e, #283593);
    color: white;
    text-decoration: none;
    border-radius: 50px;
    font-weight: 600;
    font-size: 16px;
    transition: all 0.3s ease;
    border: none;
    cursor: pointer;
}

.cta-button:hover {
    transform: translateY(-3px);
    box-shadow: 0 10px 20px rgba(26, 35, 126, 0.3);
}

.cta-button.secondary {
    background: white;
    color: #1a237e;
    border: 2px solid #1a237e;
}

.cta-button.secondary:hover {
    background: #1a237e;
    color: white;
}

/* ========== RESPONSIVE DESIGN ========== */

@media (max-width: 1024px) {
    .intro-wrapper {
        flex-direction: column;
        gap: 40px;
    }
    
    .intro-visual {
        flex: 0 0 auto;
        width: 100%;
    }
    
    .quality-analysis {
        grid-template-columns: 1fr;
        gap: 40px;
    }
}

@media (max-width: 768px) {
    .pamphlet-header h1 {
        font-size: 32px;
    }
    
    .pamphlet-header .subtitle {
        font-size: 16px;
    }
    
    .peptide-content-container {
        padding: 20px 15px;
    }
    
    .peptide-introduction,
    .content-section,
    .conclusion-section {
        padding: 30px 25px;
    }
    
    .intro-text h2,
    .section-header h2 {
        font-size: 28px;
    }
    
    .conclusion-section h2 {
        font-size: 28px;
    }
    
    .section-subtitle,
    .intro-text p,
    .conclusion-text {
        font-size: 16px;
    }
    
    .methods-grid {
        grid-template-columns: 1fr;
    }
    
    .technology-grid,
    .infrastructure-details,
    .systems-grid {
        grid-template-columns: 1fr;
    }
    
    .conclusion-cta {
        flex-direction: column;
        align-items: center;
    }
    
    .cta-button {
        width: 100%;
        justify-content: center;
    }
}

@media (max-width: 480px) {
    .pamphlet-header {
        padding: 40px 0 30px;
    }
    
    .pamphlet-header h1 {
        font-size: 28px;
    }
    
    .section-icon {
        font-size: 36px;
    }
    
    .tech-icon,
    .item-icon {
        width: 60px;
        height: 60px;
        font-size: 24px;
    }
    
    .process-step {
        flex-direction: column;
        text-align: center;
        align-items: center;
    }
    
    .step-number {
        margin-bottom: 15px;
    }
}